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Research Grants for Small Businesses — Page 4

Research and development funding where small businesses are among the recorded applicant types.

261 current opportunities · showing 73–96

OPENTechnology & Innovation

National Bycatch Reduction Engineering Program (BREP) - FY2026/27

DOC NOAA - ERA Production

This grant program provides competitive grants to non-Federal researchers working to benefit U.S. fishermen and fisheries, including aquaculture, through the development of improved fishing practices and innovative gear technologies. The Magnuson-Stevens Fishery Conservation and Management Act, as a

Deadline
Jan 23, 2027
Funding
Estimated total program funding: $4,600,000
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OPENHealth & Medical

HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required)

National Institutes of Health

The National Institutes of Health (NIH) intends to renew the Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) research network. This renewed network will include several individual research projects supported by one central Coordination Center. The goal of the network is to

Deadline
Jan 27, 2027
Funding
See official notice
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OPENNonprofit & Community Services

Specialized Alcohol Research Centers (P50 Clinical trial Optional)

National Institutes of Health

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) supports a broad-based Alcohol Research Centers program to foster and conduct interdisciplinary, collaborative research on alcohol misuse, Alcohol Use Disorder (AUD), and alcohol-related problems, and other health-related consequences across the lifespan. T

Deadline
Jan 27, 2027
Funding
Award ceiling $1,150,000
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OPENHealth & Medical

Diabetes Research Centers (P30 Clinical Trial Optional)

National Institutes of Health

This Notice of Funding Opportunity (NOFO) invites applications for Diabetes Research Centers (DRCs) that are designed to support and enhance the national research effort in diabetes, its complications, and related endocrine and metabolic diseases. The purpose of this Centers program is to bring toge

Deadline
Jan 28, 2027
Funding
Estimated total program funding: $18,200,000
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OPENSmall Business & Startups

Knowledge Transfer Partnership (KTP): 2026 - 2027 Round 4

UK Government

Description The Knowledge Transfer Partnership (KTP) programme allows a UK registered business (which we will refer to collectively as the ‘business partner’ from now on), to partner with a ‘knowledge base partner’. The knowledge base partner should be either a UK higher education (HE) or further education (FE) institu

Deadline
Jan 28, 2027
Funding
See official notice
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OPENHealth & Medical

BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed)

National Institutes of Health

Awarded activities will facilitate the translation of novel recording and modulation technologies that can be used to treat and/or diagnose central nervous system (CNS) diseases and disorders and to better understand the human CNS, from proof of concept up to the stage of readiness for first in huma

Deadline
Jan 29, 2027
Funding
Up to $750,000
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OPENHealth & Medical

Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)

National Institutes of Health

The purpose of this notice of funding opportunity (NOFO) is to support a consortium of Translational Centers using Microphysiological Systems (MPS) for Infectious Diseases (TCMID). Recent efforts in the MPS fields are moving towards validation and regulatory use but have not focused upon models studying infectious dise

Deadline
Jan 29, 2027
Funding
See official notice
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OPENHealth & Medical

Minor Use Minor Species Development of Drugs (R01)

Food and Drug Administration

This Notice of Funding Opportunity (NOFO) is issued by the Food and Drug Administration (FDA), Center for Veterinary Medicine (CVM), and solicits Research Project (R01) grant applications from institutions or organizations that propose to develop or support the development of designated new animal d

Deadline
Jan 30, 2027
Funding
Estimated total program funding: $250,000
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OPENAgriculture & Food

Agriculture Innovation Center Grant Program

Rural Business-Cooperative Service

The primary objective of the program is to provide grants to Agriculture Innovation Centers that will provide technical assistance to agricultural producers to market value-added agricultural products.

Deadline
Feb 1, 2027
Funding
Estimated total program funding: $2,500,000
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OPENEducation

BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)

National Institutes of Health

The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to encourage applications that will develop and validate novel tools to facilitate the detailed analysis of complex circuits and provide insights into cellular interactions that underlie brain fun

Deadline
Feb 9, 2027
Funding
See official notice
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OPENHealth & Medical

Neural Ensembles & Used Substances (NExUS) Collaboratory: Building a Multimodal Inventory of Cell Ensembles Encoding the Effects of Addictive Substances (U01 Clinical Trial Not Allowed)

National Institutes of Health

The National Institute on Drug Abuse (NIDA) invites applications to renew and expand the Collaboratory on Neural Ensembles and Used Substances (NExUS).NExUS is a collaborative research program to decode how substance use experiences and addictive neurobehavioral states are represented in the brain a

Deadline
Feb 9, 2027
Funding
Estimated total program funding: $4,000,000
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OPENHealth & Medical

Silvio O. Conte Digestive Diseases Research Core Centers (P30-Clinical Trial Optional)

National Institutes of Health

This Notice of Funding Opportunity (NOFO) invites applications for Silvio O. Conte Digestive Diseases Research Core Centers (DDRCCs). The DDRCCs are part of an integrated program of digestive and liver diseases research support provided by the NIDDK. The purpose of this Centers program is to bring t

Deadline
Feb 11, 2027
Funding
Estimated total program funding: $4,800,000
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OPENVeterans & Military Families

NLM Institutional Grants for Research Training in Biomedical Informatics, Data Science, and AI (T15 Independent Clinical Trial Not Allowed)

National Institutes of Health

The National Library of Medicine (NLM) invites applications for innovative predoctoral and postdoctoral training programs that prepare the next generation of researchers in biomedical informatics, data science, and artificial intelligence/machine learning (AI/ML). NLM emphasizes cutting-edge, forward-looking training e

Deadline
Feb 11, 2027
Funding
Award floor $500,000; Award ceiling $775,000
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OPENResearch & Science

BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Clinical Trial Not Allowed)

National Institutes of Health

Invasive surgical procedures in humans offer the unique opportunity to intracranially record and stimulate neuronal activity within precisely localized brain structures, enabling high-impact human neuroscience investigations. This NOFO seeks exploratory research projects, from newly formed or establ

Deadline
Feb 12, 2027
Funding
Estimated total program funding: $6,000,000
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OPENHealth & Medical

The NCI Worta McCaskill-Stevens Career Development Award for Community Oncology and Prevention Research (K12 Clinical Trial Optional)

National Institutes of Health

The purpose of the Worta McCaskill-Stevens K12 funding opportunity is to support institutional career development awards designed to prepare newly trained clinicians who have made a commitment to independent research careers in community oncology or cancer prevention, and to facilitate their transit

Deadline
Feb 19, 2027
Funding
See official notice
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OPENHealth & Medical

Supporting Talented Early Career Researchers in Genomics (R01 Clinical Trial Optional)

National Institutes of Health

This Funding Opportunity Announcement is intended to identify and support research projects by exceptionally promising Early Stage Investigators with a long-term career interest in pursuing innovative research in genomics. This opportunity is open to research in all areas relevant to the mission of

Deadline
Feb 27, 2027
Funding
See official notice
Check fit and official source →
OPENHealth & Medical

Accelerating Discovery through Partnered Research with All of Us to Analyze Participant Biospecimens (X01 Clinical Trial Not Allowed)

National Institutes of Health

The purpose of this Program Announcement with Special Receipt, Referral, and/or Review Considerations (PAR) is to solicit applications to access stored blood plasma, blood serum, and extracted DNA from the All of Us Research Program supported Biobank to advance the program's mission of accelera

Deadline
Mar 2, 2027
Funding
See official notice
Check fit and official source →
OPENSmall Business & Startups

Visa Fees Reimbursement Scheme for Scale Ups

UK Government

The visa fees reimbursement scheme for scale ups provides financial support to UK-based scale-ups operating in the Clean Energy, Life Sciences, and Digital and Technologies sectors. The scheme aims to reduce cost barriers to hire internationally, improving recruitment speed and certainty in sectors central to the UK’s

Deadline
Mar 2, 2027
Funding
See official notice
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OPENHealth & Medical

High Priority HIV and Substance Use Research (RM1 Clinical Trial Optional)

National Institutes of Health

The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of HIV and substance use. This FOA invites innovative research projects with the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention, treatment a

Deadline
Mar 6, 2027
Funding
Up to $1,500,000
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OPENHealth & Medical

Discovery of in vivo Chemical Probes for the Nervous System (R01 Clinical Trial Not Allowed)

National Institutes of Health

The purpose of this Notice of Funding Opportunity (NOFO) is to support investigators who have the interest and capability to join efforts for the discovery of in vivo chemical probes for novel brain targets. It is expected that applicants will have, in hand, the starting compounds (validated hits) f

Deadline
Mar 6, 2027
Funding
See official notice
Check fit and official source →
OPENHealth & Medical

Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional)

National Institutes of Health

The goal of this program is to support collaborative translational research projects aligned with NIH efforts to enhance the translation of basic biological discoveries into clinical applications that improve health. It encourages high quality science demonstrating the potential to result in underst

Deadline
Mar 7, 2027
Funding
Up to $500,000
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OPENHealth & Medical

High Priority HIV and Substance Use Research (R01 Clinical Trial Optional)

National Institutes of Health

The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of HIV and substance use. This FOA invites innovative research projects with the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention, treatment a

Deadline
Mar 7, 2027
Funding
See official notice
Check fit and official source →
OPENHealth & Medical

Continuation of the Cardiovascular Repository for-Type 1 Diabetes (CARE-T1D) Consortium U01 (Open Competition)- Research (U01, Clinical Trial Not Allowed)

National Institutes of Health

The NIH Cardiovascular Repository for Type 1 Diabetes (CaRe-T1D) was created to improve research on type 1 diabetes (T1D) and cardiovascular disease (CVD). Cardiovascular complications remain the top cause of death among people with T1D and greatly shorten lifespan. The mechanisms underlying atheros

Deadline
Mar 11, 2027
Funding
Estimated total program funding: $6,000,000
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OPENSmall Business & Startups

NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)

National Institutes of Health

The Small Business Technology Transfer (STTR) grant program helps United States small business concerns (SBCs) that partner with a nonprofit research institution bring scientific innovations to the marketplace. The STTR program supports feasibility studies to later stage research and development (R&

Deadline
Apr 6, 2027
Funding
See official notice
Check fit and official source →

Strong fit signals

  • The technical question is testable
  • The team can document research capability
  • Commercial impact is credible

Requirements to verify

  • Phase-specific eligibility
  • Partner and principal-investigator rules

How to use this shortlist

Open the official notice for each candidate and build a simple go/no-go table covering legal applicant type, geography, project purpose, award range, match, registrations and submission time zone. Eliminate any program that fails a mandatory condition before spending time on narrative drafting.

Frequently asked questions

Who should use this research grants for small businesses page?

Research-led small businesses and commercialization teams. Treat the directory match as a discovery signal and confirm the controlling eligibility language on the funder's notice.

How are opportunities selected?

The page applies a fixed combination of structured applicant, focus, source, award or deadline signals to current directory records. It does not broaden the result with unrelated keywords.

Does a listing mean my organization is eligible?

No. A match helps build a shortlist; the official notice, application package and funder guidance control eligibility and allowable costs.