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Community Development Grants for Nonprofits — Page 2

Community, regional and social-service funding with nonprofit eligibility signals.

241 current opportunities · showing 25–48

OPENHealth & Medical

Cellular Senescence Network (SenNet): Discovery, Validation Centers (UM1 Clinical Trials Not Allowed)

National Institutes of Health

The purpose of this Notice of Funding Opportunity (NOFO) is to support SenNet Discovery and Validation Centers (SenNet DVCs) as a core component of Stage 2 of the NIH Common Fund Cellular Senescence Network (SenNet). Building on Stage 1 resources, DVCs will define, refine, and validate tissue- and d

Deadline
Nov 24, 2026
Funding
See official notice
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OPENHealth & Medical

Cellular Senescence Network (SenNet): SenNet Technology Projects (SenTecs) (UG3/UH3 Clinical Trial Not Allowed)

National Institutes of Health

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit the development of innovative senescence technologies (SenTecs), or the adaptation of existing technologies focused on identification, characterization and understanding the biological consequences of senescent cell (SnC) heterog

Deadline
Nov 24, 2026
Funding
Estimated total program funding: $6,000,000
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OPENHealth & Medical

Cellular Senescence Network (SenNet): SenNet Data Coordination and Integration Center (SenNet DCIC) (UM1 Clinical Trials Not Allowed)

National Institutes of Health

The purpose of this Notice of Funding Opportunity (NOFO) is to support the SenNet Data Coordination and Integration Center (SenNet DCIC) as a core component of Stage 2 of the NIH Common Fund Cellular Senescence Network (SenNet). The DCIC will enable timely, high-quality submission, harmonization, in

Deadline
Nov 24, 2026
Funding
Estimated total program funding: $3,000,000
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OPENHealth & Medical

Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements (Clinical Trial Optional)

National Institutes of Health

The National Institutes of Health (NIH) hereby notifies NIH award recipients that funds may be available for revision applications to support the expansion of existing projects and/or programs within the awarding IC identified in the competitive revision Notice of Special Interest (NOSI). Applicatio

Deadline
Nov 25, 2026
Funding
See official notice
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OPENHealth & Medical

NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)

National Institutes of Health

The purpose of this notice of funding opportunity (NOFO) is to provide salary support for exceptional Research Software Engineers (RSEs) that contribute their skills to the development and dissemination of biomedical, behavioral or health related software, tools, and algorithms as well as to the tra

Deadline
Dec 5, 2026
Funding
See official notice
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OPENClimate & Environment

Great Lakes Restoration Initiative: Community Forest and Open Space Conservation Program

Forest Service

Federally recognized Indian Tribes, local government entities, and nonprofit organizations that are qualified to acquire and manage land may apply for up to $1,000,000 for the fee simple acquisition of private forest land in portions of the Lake Superior Basin of Michigan and Wisconsin. Projects sub

Deadline
Dec 9, 2026
Funding
Estimated total program funding: $3,500,000
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OPENClimate & Environment

Technical Assistance and Training Grant Program

Rural Utilities Service

Funds may be used to pay expenses associated with providing technical assistance and/or training (TAT) to: Identify and evaluate solutions to water problems relating to source, storage, treatment, or distribution; identify and evaluate solutions to waste problems relating to collection, treatment, o

Deadline
Jan 1, 2027
Funding
Estimated total program funding: $35,000,000
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OPENEducation

National Parks Business Plan Internship

National Park Service

The National Parks Business Plan Internship (BPI) goal is to jointly administer a graduate-level internship program focused on improving the business management and operational health of our national parks and NPS programs. The internship program should:Provide students with in-depth training on NPS

Deadline
Jan 5, 2027
Funding
Estimated total program funding: $1,700,000
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OPENHealth & Medical

Interventions to expand cancer screening and preventive services to ADVANCE health in populations that experience health disparities (R01, Clinical Trial Required)

National Institutes of Health

The Office of Disease Prevention (ODP) and participating National Institutes of Health (NIH) Institutes, Centers, and Offices (ICs) are issuing this R01 to solicit applications to address barriers and facilitators that impede use or uptake of cancer screening and preventive services in populations t

Deadline
Jan 8, 2027
Funding
See official notice
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OPENHealth & Medical

Academic-Industrial Partnerships (AIP) to Translate and Validate In Vivo Imaging Systems (R01 Clinical Trial Optional)

National Institutes of Health

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to stimulate translation of scientific discoveries and engineering developments in imaging, data science and/or spectroscopic technologies into methods or tools that address contemporary problems in unders

Deadline
Jan 8, 2027
Funding
Estimated total program funding: $500,000
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OPENHealth & Medical

Population Approaches to Reducing Alcohol-related Cancer Risk (R01 Clinical Trial Optional)

National Institutes of Health

This Notice of Funding Opportunity (NOFO) aims to support research on interdisciplinary population approaches to increasing awareness of the relationship between alcohol and cancer risk, understanding and changing social norms related to alcohol consumption, developing and/or evaluating alcohol poli

Deadline
Jan 8, 2027
Funding
See official notice
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OPENHealth & Medical

National Cancer Institute's Investigator-Initiated Early Phase Clinical Trials for Cancer Treatment and Diagnosis (R01 Clinical Trial Required)

National Institutes of Health

Through this Notice of Funding Opportunity, the National Cancer Institute (NCI) seeks research projects that implement early phase (Phase 0, I, and II) investigator-initiated clinical trials focused on cancer-targeted diagnostic and therapeutic interventions of direct relevance to the research missi

Deadline
Jan 8, 2027
Funding
Estimated total program funding: $499,999
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OPENHealth & Medical

Cancer Prevention and Control Clinical Trials Grant Program (R01 Clinical Trial Required)

National Institutes of Health

Through this notice of funding opportunity (NOFO), the National Cancer Institute (NCI) invites applications for support of investigator-initiated clinical trials that have the potential to reduce the burden of cancer through improvements in early detection, screening, prevention and interception, he

Deadline
Jan 8, 2027
Funding
See official notice
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OPENEducation

Developing novel theory and methods for understanding the genetic architecture of complex human traits (R21 Clinical Trial Not Allowed)

National Institutes of Health

The goal of this NOFO is to support R21 applications for novel theory and methods development that better delineate how genetic and non-genetic factors contribute to complex trait variation across individuals, families, and populations. Approaches should be interdisciplinary across the natural and s

Deadline
Jan 8, 2027
Funding
See official notice
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OPENHealth & Medical

Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R21 Clinical Trial Not Allowed)

National Institutes of Health

The goal of the proposed funding announcement is twofold, to promote preclinical and patient based studies examining the mechanism(s) through which incretin mimetics (including agonists or antagonists of GLP-1, GIP-1, or dual GLP-1/GIP-1 agents) impact cancer risk, and to draw talented scientists wh

Deadline
Jan 8, 2027
Funding
See official notice
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OPENHealth & Medical

Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R01 Clinical Trial Optional)

National Institutes of Health

The goal of the proposed funding announcement is twofold, to promote preclinical and patient based studies examining the mechanism(s) through which incretin mimetics (including agonists or antagonists of GLP-1, GIP-1, or dual GLP-1/GIP-1 agents) impact cancer risk, and to draw talented scientists wh

Deadline
Jan 8, 2027
Funding
See official notice
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OPENHealth & Medical

Personal Health Informatics for Delivering Actionable Insights to Individuals (R01 Clinical Trial Optional)

National Institutes of Health

The purpose of this Notice of Funding Opportunity (NOFO) is to advance the development of novel informatics and data science approaches that can help individuals understand and improve their health through actionable insights. NLM seeks applications that further the science of personal health inform

Deadline
Jan 8, 2027
Funding
Up to $250,000
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OPENHealth & Medical

Prevention and Intervention Approaches for Fetal Alcohol Spectrum Disorders (R34 Clinical Trial Optional)

National Institutes of Health

This Notice of Funding Opportunity (NOFO) for R34 planning grant applications focuses on prevention and intervention strategies for fetal alcohol spectrum disorders (FASD) throughout the lifespan. The intent of this NOFO is to support research that advances (1) prevention approaches to reduce prenat

Deadline
Jan 8, 2027
Funding
See official notice
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OPENHealth & Medical

Accelerating Solutions to Improve Access and Quality of Empirically-Supported Practices for Youth Mental Health (R01 Clinical Trial Optional)

National Institutes of Health

This NOFO is a call to action in response to the mental health crisis in the United States. We seek applications that will study methods to increase access to evidence-based interventions and services for youth mental health, including those living in rural areas, inner cities, and other under-resou

Deadline
Jan 8, 2027
Funding
See official notice
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OPENHealth & Medical

NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)

National Institutes of Health

The objective of this funding opportunity is to support investigator-initiated, Phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders in adults and children. In addition to supporting clinical trial start-up and implementation activit

Deadline
Jan 8, 2027
Funding
See official notice
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OPENHealth & Medical

NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)

National Institutes of Health

The objective of this funding opportunity is to support investigator-initiated, phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders in adults and children. The proposed trial can be single or multisite. Applicants applying for fundi

Deadline
Jan 8, 2027
Funding
Up to $1,515,000
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OPENHealth & Medical

NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)

National Institutes of Health

This Notice of Funding Opportunity Announcement (NOFO) intends to supports studies that are both necessary and sufficient to inform the planning of a Phase II-IV clinical trial within NHLBI's mission. The NHLBI expects that applications to this NOFO will describe the planned clinical trial and

Deadline
Jan 8, 2027
Funding
See official notice
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OPENHealth & Medical

Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)

National Institutes of Health

The purpose of this notice of funding opportunity (NOFO) is to support research on interventions to improve health in Native American (NA) populations. This includes 1) etiologic research, where there is a significant gap in knowledge, that will directly inform intervention development or adaptation

Deadline
Jan 8, 2027
Funding
See official notice
Check fit and official source →

Strong fit signals

  • The service area is clearly defined
  • Community need is supported by recent evidence
  • Delivery partners have named roles

Requirements to verify

  • Geographic restrictions
  • Required match and post-award reporting

How to use this shortlist

Open the official notice for each candidate and build a simple go/no-go table covering legal applicant type, geography, project purpose, award range, match, registrations and submission time zone. Eliminate any program that fails a mandatory condition before spending time on narrative drafting.

Frequently asked questions

Who should use this community development grants for nonprofits page?

Nonprofits delivering place-based community outcomes. Treat the directory match as a discovery signal and confirm the controlling eligibility language on the funder's notice.

How are opportunities selected?

The page applies a fixed combination of structured applicant, focus, source, award or deadline signals to current directory records. It does not broaden the result with unrelated keywords.

Does a listing mean my organization is eligible?

No. A match helps build a shortlist; the official notice, application package and funder guidance control eligibility and allowable costs.