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Core Research in Biological Sciences (BIO Core)

U.S. National Science Foundation

The U.S. National Science Foundation's Directorate for Biological Sciences (NSF BIO) Core Research in Biological Sciences (BIO Core) funding opportunity supports foundational and interdisciplinary research projects that expand knowledge of biology at any level of organization, from the molecula

Funding
Estimated total program funding: $280,000,000
Category
Research & Science
Status
OPEN
Deadline
8/22/2076

About

The U.S. National Science Foundation's Directorate for Biological Sciences (NSF BIO) Core Research in Biological Sciences (BIO Core) funding opportunity supports foundational and interdisciplinary research projects that expand knowledge of biology at any level of organization, from the molecular to the biome scale. We accept proposals that cover scientific topics associated with legacy programs historically supported by NSF BIO and proposals that explore new areas of biological sciences.BIO Core funds single- and multi-investigator awards. The portfolio of awards is anticipated to include a range of budgets and durations, including exploratory projects of smaller scope and long-horizon projects that benefit from longer-term commitment. BIO Core awards are subject to the availability of funds.

Eligibility

*Who May Submit Proposals: Proposals may only be submitted by the following: -Non-profit, non-academic organizations: Independent museums, observatories, research laboratories, professional societies and similar organizations located in the U.S. that are directly associated with educational or research activities. -Institutions of Higher Education (IHEs): Two- and four-year IHEs (including community colleges) accredited in, and having a campus located in the US, acting on behalf of their faculty members. Special Instructions for International Branch Campuses of US IHEs: If the proposal includes funding to be provided to an international branch campus of a US institution of higher education (including through use of sub-awards and consultant arrangements), the proposer must explain the benefit(s) to the project of performance at the international branch campus, and justify why the project activities cannot be performed at the US campus. -Tribal Nations: An American Indian or Alaska Native tribe, band, nation, pueblo, village, or community that the Secretary of the Interior acknowledges as a federally recognized tribe pursuant to the Federally Recognized Indian Tribe List Act of 1994, 25 U.S.C. §§ 5130-5131.

Applicant types

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Juvenile Sportfish Community and Habitat Suitability in Florida Bay

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1) Note: A full study proposal and proposed budget are NOT requested at this time.2) Project Title: Juvenile Sportfish Community and Habitat Suitability in Florida Bay3) Brief Description of Anticipated Work: See Attached SOO4) Period of Performance: Base period: 12 months from date of award. Follow

American Alligators as Ecological Indicators of Everglades Restoration

Fort Worth District

1) Note: A full study proposal and proposed budget are NOT requested at this time.2) Project Title: American Alligators as Ecological Indicators of Everglades Restoration.3) Brief Description of Anticipated Work: See Attached SOO for more information.4) Period of Performance: Base period: 12 months

Wading Bird Response to Ecosystem Restoration in Southwest Florida

Fort Worth District

1) Note: A full study proposal and proposed budget are NOT requested at this time.2) Project Title: Wading Bird Response to Ecosystem Restoration in Southwest Florida.3) Brief Description of Anticipated Work: See attached SOO for this information.4) Period of Performance: Base period: 12 months from

American Crocodile Monitoring as an Indicator of Hydrologic Restoration in the Southern Estuaries for the U.S. Army Corps of Engineers, Jacksonville District.

Fort Worth District

1) Note: A full study proposal and proposed budget are NOT requested at this time.2) Project Title: American Crocodile Monitoring as an Indicator of Hydrologic Restoration in the Southern Estuaries for the U.S. Army Corps of Engineers, Jacksonville District.3) Brief Description of Anticipated Work:

Notice-specific evidence check

What an applicant must verify for Core Research in Biological Sciences (BIO Core)

Applicant evidence

  • Applicant type: Other eligible applicants

Opportunity boundaries

  • Recorded funding: Estimated total program funding: $280,000,000
  • Recorded deadline: August 22, 2076; confirm time zone and submission system.
  • Recorded focus: Science, technology and research
Before investing in an application, connect every eligibility claim, required registration, submission component and deadline to the current official notice. Open the recorded official source →

Application checklist

How to apply for Core Research in Biological Sciences (BIO Core)

The steps below turn the recorded grant fields into a pre-submission check. They do not replace the current Notice of Funding Opportunity or its amendments.

Recorded eligibility

  • • Applicant types: Grants.gov eligibility code 25.
  • • Geographic scope is not structured in this record.
  • • Notice summary: *Who May Submit Proposals: Proposals may only be submitted by the following: -Non-profit, non-academic organizations: Independent museums, observatories, research laboratories, professional societies and similar organizations located in the U.S. that are directly associated with educational or research activities. -Institutions of Higher Education (IHEs): Two- and four-year IHEs (including community colleges) accredited in, and having a campus located in the US, acting on behalf of their faculty members. Special Instructions for International Branch Campuses of US IHEs: If the proposal includes funding to be provided to an international branch campus of a US institution of higher education (including through use of sub-awards and consultant arrangements), the proposer must explain the benefit(s) to the project of performance at the international branch campus, and justify why the project activities cannot be performed at the US campus. -Tribal Nations: An American Indian or Alaska Native tribe, band, nation, pueblo, village, or community that the Secretary of the Interior acknowledges as a federally recognized tribe pursuant to the Federally Recognized Indian Tribe List Act of 1994, 25 U.S.C. §§ 5130-5131.

Focus areas: ST

Recorded deadline

August 21, 2076 — confirm the time zone and submission system

A missing or rolling date is not permission to assume an open application window.

  1. 1. Confirm fitMatch your applicant type, location, project scope and any cost-share or registration rule to the official notice.
  2. 2. Read the noticeCollect the current guidelines, amendments, budget rules, required attachments and submission instructions.
  3. 3. Check timingRecord the deadline time zone, internal review date and any earlier registration or portal cut-off.
  4. 4. Submit thereUse the official application route and save the confirmation or submission reference.

Official sources

Recorded source: https://www.grants.gov/xml-extract

Last directory verification: Oct 2, 2026.