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Limited Competition for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Clinical Centers (U01 Clinical Trial Required)

National Institutes of Health

This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-revi

Funding
Estimated total program funding: $1,850,000
Category
Health & Medical
Status
OPEN
Deadline
11/7/2026

About

This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding. This NOFO requests limited competition applications for a 3-year extension of the COPE-AKI clinical trial consortium, which includes three clinical centers (CCs) and one scientific and data research center (SDRC), to fully meet the enrollment targets, complete participant follow-up, and provide resources for data analysis and dissemination of study findings. There is currently no standard of care for patients after hospitalization with acute kidney injury (AKI). Successful completion of the COPE-AKI study will provide key insights that are expected to directly inform improved clinical management strategies and the development of standard of care for Stage 2 and 3 AKI survivors.

Eligibility

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.As this NOFO is a Limited Competition, only the current recipients under RFA-DK-20-011 are eligible to apply under this announcement.As this NOFO is a limited competition opportunity, only the institutions that are the principal employer of the Program Director/Principal Investigator of the original COPE-AKI Participating Clinical Centers and the COPE-AKI Scientific Data Research Center are eligible to apply in response to this NOFO.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Applicant types

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Notice-specific evidence check

What an applicant must verify for Limited Competition for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Clinical Centers (U01 Clinical Trial Required)

Applicant evidence

  • Applicant type: Grants.gov eligibility code 25

Opportunity boundaries

  • Recorded funding: Estimated total program funding: $1,850,000
  • Recorded deadline: November 7, 2026; confirm time zone and submission system.
  • Recorded focus: Health
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