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NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed)

This Notice of Funding Opportunity (NOFO) will support, through the cooperative agreement mechanism, investigator-initiated observational studies or biomarker validation studies that require prospective collection of data/biospecimens or continued analysis of data/biospecimens.

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Funding: Up to $500,000
Deadline: July 6, 2029
Status: OPEN
Category: Health & Medical
Opens: June 16, 2026
Directory link check: October 27, 2026

About this opportunity

Eligibility recorded

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility. Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Applicant types

State governments County governments City or township governments Special district governments Independent school districts Public and state-controlled institutions of higher education Federally recognized tribal governments Public housing authorities and Indian housing authorities Native American tribal organizations 501(c)(3) nonprofits other than higher-education institutions Nonprofits without 501(c)(3) status other than higher-education institutions Private institutions of higher education For-profit organizations other than small businesses Small businesses Other eligible applicants

Focus areas

Health

Recorded notice evidence

What to verify for NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed)

Applicant evidence

Applicant type: State governments
Applicant type: County governments
Applicant type: City or township governments
Applicant type: Special district governments
Applicant type: Independent school districts
Applicant type: Public and state-controlled institutions of higher education
Applicant type: Federally recognized tribal governments
Applicant type: Public housing authorities and Indian housing authorities

Opportunity boundaries

Recorded funding: Up to $500,000
Recorded deadline: July 6, 2029; confirm the closing time.
Recorded focus: Health

Connect every eligibility claim, registration, attachment and deadline to the current notice. Open the specific official notice →

Application checklist

How to evaluate and apply for NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed)

Use this record for discovery, then connect every requirement and date to the current official notice and its amendments.

Recorded applicant fit

State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and state-controlled institutions of higher education

Recorded geography

No structured geographic scope is recorded.

Recorded deadline

July 6, 2029 — confirm the closing time.

Eligibility summary: Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility. Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Recorded focus: Health

1Confirm fitMatch entity type, location, project scope, exclusions and cost share.

2Read the noticeCollect amendments, budget rules, attachments and portal instructions.

3Plan timingRecord the funder’s time zone, registrations and internal review dates.

4Submit officiallyUse the funder’s route and save the submission confirmation.

Official sources

Directory link check: October 27, 2026. Always recheck the live notice before relying on it.

Open specific official notice →

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