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Limited Competition: Intellectual and Developmental Disabilities Research Centers 2027 (P50 Clinical Trial Optional)

National Institutes of Health

This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Section III. Eligibility for additional information. The purpose of this NOFO is to seek applications in a limited competition for the Eunice Ke

Funding
Estimated total program funding: $18,000,000
Category
Health & Medical
Status
OPEN
Deadline
10/3/2026

About

This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Section III. Eligibility for additional information. The purpose of this NOFO is to seek applications in a limited competition for the Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Centers (IDDRCs). This NOFO invites applications to undergo peer review for research center grants designed to advance the diagnosis, prevention, treatment, and amelioration of intellectual and developmental disabilities (IDD) and is limited to IDDRCs funded under RFA-HD-20-016 or RFA-HD-21-009. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.This NOFO seeks applications from institutions that meet the qualifications for a multidisciplinary program of IDD research that will include: 1) 3-4 total Cores that facilitate interdisciplinary and translational research in IDD and its dissemination, and that support IDD-related projects funded by other sources; and 2) at least two and no more than three specific research projects related to one of several areas identified as areas of research need in IDD. Collaborative investigations combining expertise in translational science, biomarker assessment, outcome measure development, tool validation, bioinformatics, and therapeutic development will be encouraged. Funds for the majority of outside research projects using these core facilities come from independent sources including Federal, State, and private organizations. In addition, the Center should include plans for outreach, engagement, and dissemination to the community, including persons with lived experience (PWLE) of disabilities. The duration of these Centers will be 3 years in total.

Eligibility

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.This competition is limited to applicants that are recipients of IDDRC P50 awards under RFA-HD-20-016 or RFA-HD-21-009. Please refer to Section 1. Notice of Funding Opportunity Information for more details.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Applicant types

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Notice-specific evidence check

What an applicant must verify for Limited Competition: Intellectual and Developmental Disabilities Research Centers 2027 (P50 Clinical Trial Optional)

Applicant evidence

  • Applicant type: Other eligible applicants

Opportunity boundaries

  • Recorded funding: Estimated total program funding: $18,000,000
  • Recorded deadline: October 3, 2026; confirm time zone and submission system.
  • Recorded focus: Health
Before investing in an application, connect every eligibility claim, required registration, submission component and deadline to the current official notice. Open the recorded official source →

Application checklist

How to apply for Limited Competition: Intellectual and Developmental Disabilities Research Centers 2027 (P50 Clinical Trial Optional)

The steps below turn the recorded grant fields into a pre-submission check. They do not replace the current Notice of Funding Opportunity or its amendments.

Recorded eligibility

  • Applicant types: Grants.gov eligibility code 25.
  • Geographic scope is not structured in this record.
  • Notice summary: Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.This competition is limited to applicants that are recipients of IDDRC P50 awards under RFA-HD-20-016 or RFA-HD-21-009. Please refer to Section 1. Notice of Funding Opportunity Information for more details.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Focus areas: HL

Recorded deadline

October 2, 2026 — confirm the time zone and submission system

A missing or rolling date is not permission to assume an open application window.

  1. 1. Confirm fitMatch your applicant type, location, project scope and any cost-share or registration rule to the official notice.
  2. 2. Read the noticeCollect the current guidelines, amendments, budget rules, required attachments and submission instructions.
  3. 3. Check timingRecord the deadline time zone, internal review date and any earlier registration or portal cut-off.
  4. 4. Submit thereUse the official application route and save the confirmation or submission reference.

Official sources

Recorded source: https://www.grants.gov/xml-extract

Last directory verification: Sep 13, 2026.