OPENVerified record

Effectiveness Trials to Test Mental Health System Interventions (R61/R33 Clinical Trial Required)

Visit official funding page →How we check listings

Funding: See official notice
Deadline: October 16, 2027
Status: OPEN
Category: Health & Medical
Opens: November 26, 2024
Directory link check: October 27, 2026

About this opportunity

This R61/R33 concept complements NIMHs suite of clinical trial NOFOs by supporting feasibility and infrastructure development (R61) followed by well-powered clinical trials (R33) to test the effectiveness of system interventions and strategies for improving the organization, delivery, coordination, and clinical and functional outcomes of mental health services. System interventions - which may span, for example, structural, policy, organizational, and interpersonal domains - attend to issues about the access, equity, engagement/utilization, value (cost/financing), management, or quality and safety of mental health services, with the goal of improved care processes and clinical and functional outcomes. Accordingly, the focus of system interventions may include a variety of care settings, such as health systems and organizations, mental health and community clinics, schools, and child welfare or juvenile justice systems

Eligibility recorded

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Applicant types

State governments County governments City or township governments Special district governments Independent school districts Public and state-controlled institutions of higher education Federally recognized tribal governments Public housing authorities and Indian housing authorities Native American tribal organizations 501(c)(3) nonprofits other than higher-education institutions Nonprofits without 501(c)(3) status other than higher-education institutions Private institutions of higher education For-profit organizations other than small businesses Small businesses Other eligible applicants

Focus areas

Health

Recorded notice evidence

What to verify for Effectiveness Trials to Test Mental Health System Interventions (R61/R33 Clinical Trial Required)

Applicant evidence

Applicant type: State governments
Applicant type: County governments
Applicant type: City or township governments
Applicant type: Special district governments
Applicant type: Independent school districts
Applicant type: Public and state-controlled institutions of higher education
Applicant type: Federally recognized tribal governments
Applicant type: Public housing authorities and Indian housing authorities

Opportunity boundaries

Recorded funding: See official notice
Recorded deadline: October 16, 2027; confirm the closing time.
Recorded focus: Health

Fields to verify directly: funding amount. A missing directory value does not remove a restriction.

Connect every eligibility claim, registration, attachment and deadline to the current notice. Open the specific official notice →

Application checklist

How to evaluate and apply for Effectiveness Trials to Test Mental Health System Interventions (R61/R33 Clinical Trial Required)

Use this record for discovery, then connect every requirement and date to the current official notice and its amendments.

Recorded applicant fit

State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and state-controlled institutions of higher education

Recorded geography

No structured geographic scope is recorded.

Recorded deadline

October 16, 2027 — confirm the closing time.

Eligibility summary: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Recorded focus: Health

1Confirm fitMatch entity type, location, project scope, exclusions and cost share.

2Read the noticeCollect amendments, budget rules, attachments and portal instructions.

3Plan timingRecord the funder’s time zone, registrations and internal review dates.

4Submit officiallyUse the funder’s route and save the submission confirmation.

Official sources

Directory link check: October 27, 2026. Always recheck the live notice before relying on it.

Open specific official notice →

Continue researching

Related current grants

All Health & Medical grants →

OPENHealth & Medical

OJJDP FY 2026 Juvenile Drug Treatment Court Program

Office of Juvenile Justice Delinquency Prevention

This is a notice of funding opportunity (NOFO) for the OJJDP FY 2026 Juvenile Drug Treatment Court Program. This opportunity will support states, state and local courts, units of local government, and federally recognized Tribal governments to implement new or enhance existing juvenile drug treatmen

Deadline: Oct 30, 2026
Funding: Estimated total program funding: $4,000,000

Check fit and official source →

OPENHealth & Medical

BJA FY 2026 Adult Treatment Court Program

Bureau of Justice Assistance

This is a notice of funding opportunity (NOFO) for the BJA FY2026 Adult Treatment Court Program. This opportunity supports the implementation and enhancement of Adult Treatment Court (ATC) operations to prevent overdoses and reduce the use of opioids, stimulants, and other substances by high-risk/hi

Deadline: Oct 31, 2026
Funding: Up to $2,500,000

Check fit and official source →

OPENHealth & Medical

HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required)

National Institutes of Health

The NIH Helping to End Addiction Long-term® (HEAL) Initiative is releasing this Notice of Funding Opportunity (NOFO) to support a phased mechanistic clinical research program focusing on understudied biological mechanisms that drive joint pain. The phased projects supported by this program (of

Deadline: Oct 31, 2026
Funding: See official notice

Check fit and official source →

OPENHealth & Medical

GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed)

National Institutes of Health

The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying

Deadline: Oct 31, 2026
Funding: Estimated total program funding: $2,000,000

Check fit and official source →